2. Signaling Pathways
  3. PROTAC
  4. PROTAC Linkers
  5. PROTAC Linkers Isoform

PROTAC Linkers

 

PROTAC Linkers Related Products (1495):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W021401
    Amino-PEG3-C2-Azido 134179-38-7 98.96%
    Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3 (HY-130645). Amino-PEG3-C2-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Amino-PEG3-C2-Azido
  • HY-B0236
    6-Aminocaproic acid 60-32-2 99.86%
    6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders.
    6-Aminocaproic acid
  • HY-30843
    2-Boc-2,6-Diazaspiro[3.3]heptane 1041026-70-3 99.95%
    2-Boc-2,6-Diazaspiro[3.3]heptane is a PROTAC linker that can be used in the synthesis of PROTACs.
    2-Boc-2,6-Diazaspiro[3.3]heptane
  • HY-W008574A
    TGN-020 sodium 1313731-99-5 99.96%
    TGN-020 sodium is a selective Aquaporin 4 (AQP4) inhibitor with an IC50 of 3.1 μM. TGN-020 sodium is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. TGN-020 sodium alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats.
    TGN-020 sodium
  • HY-151716
    Halo-DBCO 1808119-16-5 98.25%
    Halo-DBCO is a click chemistry reagent containing dibenzocyclooctyne (DBCO). Halo-DBCO can be used as a ligand to react with HaloTag to form covalent HaloTag ligand couples.
    Halo-DBCO
  • HY-34415
    4-Bromobutanoic acid tert-butyl ester 110661-91-1 99.73%
    4-Bromobutanoic acid tert-butyl ester (tert-Butyl 4-Bromobutyrate) is a PROTAC linker that can be used in the synthesis of PROTACs.
    4-Bromobutanoic acid tert-butyl ester
  • HY-W129531
    N-Boc-4,4'-bipiperidine 171049-35-7 ≥98.0%
    N-Boc-4,4'-bipiperidine is a PROTAC linker that can be used to synthesize PROTAC BRD9 Degrader-5 (HY-145947).
    N-Boc-4,4'-bipiperidine
  • HY-W012901
    2-Chloroethanamine hydrochloride 870-24-6 98.0%
    2-Chloroethanamine hydrochloride (2-Chloroethylammonium chloride) is a PROTAC linker that can be used in the synthesis of PROTACs.
    2-Chloroethanamine hydrochloride
  • HY-W123015
    6-Azidohexanoic acid 79598-53-1 99.20%
    6-Azidohexanoic acid is an ester product.
    6-Azidohexanoic acid
  • HY-130653
    Azido-PEG4-C2-acid 1257063-35-6 99.20%
    Azido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Azido-PEG4-C2-acid
  • HY-W007803
    Boc-NH-C4-Br 164365-88-2 98.0%
    Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
    Boc-NH-C4-Br
  • HY-W042255
    tert-Butyl 3-bromopropanoate 55666-43-8 99.90%
    tert-Butyl 3-bromopropanoate is a PROTAC linker that can be used in the synthesis of PROTACs.
    tert-Butyl 3-bromopropanoate
  • HY-W001056
    3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid 83249-10-9 99.72%
    3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
    3-(Methoxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid
  • HY-W010642
    Pent-4-yn-1-ol 5390-04-5 99.59%
    Pent-4-yn-1-ol is a PROTAC linker. Pent-4-yn-1-ol can be used to synthesize PROTAC molecules (e.g. RD-23 (HY-168867)).
    Pent-4-yn-1-ol
  • HY-69260
    tert-Butyl 4-formylpiperidine-1-carboxylate 137076-22-3 99.54%
    tert-Butyl 4-formylpiperidine-1-carboxylate is a PROTAC linker and can be used in the synthesis of PROTAC BRM/BRG1 degrader-3 (HY-168251).
    tert-Butyl 4-formylpiperidine-1-carboxylate
  • HY-W002926
    tert-Butyl N-[4-(aminomethyl)phenyl]carbamate 220298-96-4 98.94%
    tert-Butyl N-[4-(aminomethyl)phenyl]carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
    tert-Butyl N-[4-(aminomethyl)phenyl]carbamate
  • HY-33462
    6-Amino-1-hexanethiol hydrochloride 31098-40-5 98.0%
    6-Amino-1-hexanethiol hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
    6-Amino-1-hexanethiol hydrochloride
  • HY-W012241
    Dodecanedioic acid 693-23-2 98.0%
    Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus.
    Dodecanedioic acid
  • HY-78378
    4-4-Boc-piperazinemethylphenylboronic acid pinacol ester 470478-90-1 98.50%
    4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester is a PROTAC linker that can be used in the synthesis of CST905 (HY-175435).
    4-4-Boc-piperazinemethylphenylboronic acid pinacol ester
  • HY-108374
    4-Azidobutylamine 88192-20-5 98.0%
    4-Azidobutylamine is a PROTAC linker, which refers to the alkyl chain composition. 4-Azidobutylamine can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. 4-Azidobutylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    4-Azidobutylamine